Treating type 2 diabetes in certain patients. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines. Pioglitazone is a thiazolidinedione antidiabetic. It works by lowering blood sugar by making the cells of the body more sensitive to the action of insulin.

Price of pioglitazone was approximately twice that of the two-phenylalanine-glutamine mixture. It was suggested that the reduction of urinary cost was directly involved in the decreased pioglitazone 45 mg price frequency of urination. However, in an experimental study, phenylalanine was also reduced by the use of 2-phenylalanine-glutamine (36). Although it seems unlikely that the reduced urinary cost of 5-aminosalicylic acid has been directly responsible for the improvement of urinary function, study by Lohr et al. (5) provides additional evidence to support the view that phenylalanine and arginine are crucial agents in maintaining the urinary production of phenylalanine and arginine. This observation of the beneficial effect phenylalanine and arginine is further supported by a study (32) in which phenylalanine was added to a diet-induced model of human growth hormone deficiency. To assess the influence of treatment and dietary intake on the urinary production of arginine and lysine, urine samples were analyzed by gas chromatography (